Endocrine Abstracts

Long fasting in patients with adrenal insufficiency could cause hypotension, dehydration or hypoglycaemia. No studies evaluated these risks and there is no recommendations about fasting for these patients. The aim of our study was to evaluate the potential risks of fasting during the month of Ramadan in patients with adrenal insufficiency.Subjects and methods: It is a cross sectional study that concerned 125 subjects (97 women and 28 men, mean age=47.8 y...

Introduction: The main objective in the management of primary hypothyroidism is to normalize thyrotropin (TSH) level with Levothyroxine replacement therapy. The optimal dose of Levothyroxine may be affected by several factors such as age, gender, body weight, some medical disorders and drugs intake. The aim of this study was to assess the relationship between thyroid antibody titers and Levothyroxine dose in patients with primary hypothyroidism secondary to Hashimoto thyroidit...

The risk of hypotension during Ramadan fasting in patients with adrenal insufficiency is unknown. The aim of our study was to evaluate objectively this risk.Methods: It is a prospective case-crossover study on 28 patients with known and treated AI. Patients had no hypertension and were regular fasters. All patients underwent a clinical examination and a 24-hours blood pressure monitoring during Ramadan fasting then outside fasting....

Introduction: Fahr syndrome is a rare entity characterized by the presence of bilateral intracranial calcifications with predilection for the basal ganglia and dentate nuclei. It is commonly associated with endocrine disorders, particularly parathyroid and Vitamin D disturbances. Herein we report a case of pseudohypoparathyroidism revealed by Fahr syndrome.Observation: A 29-old-year male was referred to our department for symptomatic hypocalcemia. He sho...

Introduction: Diabetic foot disease is a major health problem. The identification of its risk factors should guide preventive measures. The aim of this study was to determine the factors associated with diabetic foot complications.Patients and methods: It is a retrospective study including 47 patients admitted at the department of Endocrinology in La Rabta hospital for diabetic foot complications during the years 2015 and 2016. Clinical and para-clinical...

Introduction: Although the association between parathyroid and thyroid diseases is not uncommon, the coexisting of parathyroid adenoma causing primary hyperparathyroidism (PHPT) and papillary thyroid carcinoma (PTC) is rare. Probably this can be partially explained by different embryologic origin of thyroid and parathyroid cells. Herein, we report a case of PHPT associated with synchronous bifocal PTC.Observation: A 65-year-old woman was referred to our ...

Introduction: The involvement of the thyroid gland by tuberculosis is extremely uncommon even in countries in which tuberculosis is endemic. In the majority of the reported cases, thyroid function was preserved. Herein we report a case of thyroid tuberculosis in a patient with a primary hypothyroidism.Case report: A 52-year-old woman was referred to our department for a gradually growing goiter without compressive symptoms. She presented with a productiv...

Introduction: Abnormalities in the development and migration of the thyroid gland are known to produce ectopic thyroid tissue, usually in the midline between the tongue base and the diaphragm. Hashimoto’s thyroiditis involving ectopic thyroid tissue is particularly unusual. Herein we report a case of Hashimoto’s thyroiditis developing in a midline thyroid cervical mass.Observation: A 55-year-old man was referred for hypothyroidism. His physical...

Introduction: Atrial flutter (AFL) is a rapid, regular atrial tachyarrhythmia that occurs most commonly in patients with underlying structural heart disease. Patients with tachyarrythmias as a result of thyroid storm have been typically treated with beta-blockers to decrease the heart rate and alleviate beta-receptor mediated symptoms. We report an unusual case of AFL with 1:1 atrioventricular (AV) conduction.Case report: Patient H, M 45 years old was ad...

Background: Cardiothyreosis (CT) or thyrotoxic heart is associated with higher morbidity and mortality than the other forms of hyperthyroidism. Its risk factors have been investigated in a limited number of studies. The aim of our study was to identify risk factors of CT in patients with hyperthyroidism.Methods: We identified 538 patients with a hospital discharge diagnosis of hyperthyroidism from January 2000 to December 2015. Thirty five patients were ...